After US-27 leaves downtown Miami FL where it has its southern origin, it goes NW towards the edge of the Everglades in Miami-Dade County. It then is an interior route through the middle of Florida, skirting Lake Okeechobee and is a major route for the farm products leaving FL to markets and food production facilities. Because of the nature of huge farm-product trucks constantly plying the road, and the use by travelers going long distances north and south in FL, there are often horrific accidents involving big trucks and not-so-big passenger vehicles. Many are head-on, where one driver or the other falls-asleep, crosses the centerline, and you can imagine the rest. For that reason, the road has for decades had the nickname, "Bloody 27."
I'm not an 'over-the-road' biker but when I retire, one of the trips I want to take is to travel on US 27 from FL to MI, at least for a significant part of the trip, instead of just shooting north on I-75. You travel through many smaller more-rural communities, and I think it would be an interesting way to see life away from the interstates.
Having posted about US-27 here in the past, I researched its current state, and was dismayed to see the information that 'Redbone' mentioned here. You would think that the government would want to use the roadways as a way to preserve the heritage of travel in the USA. United States Route Twenty-Seven deserves a better fate than to be dissolved as a path from the Atlantic Ocean/Biscayne Bay FL where it begins, into the heartland of the Great Lakes.