Sean's 12347 reference is that the 'overdrive' swap gearset establishes a huge gap in the top ratio. It would be of interest to someone who is using their VMax for touring, which is not the intended use of the bike. As has been mentioned, for having a ~149 mph top speed, there is plenty of 'motor' to carry whatever speed you can cruise at. Just lessening the rpm's may make things more-serene, but that large of a gap isn't going to entice the average VMax owner to make the swap.
Between the Venture or Royal Star 5th gear swap, and the final drive unit from the same, you can get better cruising rpm reduction, if that is your 'holy grail.' Hitting 9000 rpm in 4th w/a stock gearbox is going to put you in the vicinity of 130 mph I would assume, plenty fast enough for most people. It makes the gap into top gear, somewhat moot.
Another idea would be to go to chain drive, and then you can swap sprockets to your heart's content.