The Pat's D will be key in this game, if they can get to/ move Mahomes enough to keep him from getting comfortable. He will still make some plays while moving but not as much if he has time to survey and throw to Hill/ Kelce. Brady will get his team down the field because the Chiefs defense is beatable I believe. As usual he will have a mix match group of players, Gronk is a step or two slower these days but he has Edelman who is a tough SOB that can catch/ hold the ball to keep drives moving. One bright spot last week was Michele/ White, they could prove to be key in keeping the Chiefs defensive line off balance enough to give Brady some precious time to keep his eyes downfield.
Here is a quote from SBNation: "A key to beating the Chiefs, or keeping the game close, is not getting away from your game plan when things go awry, like being down early. Running the ball against the Chiefs is the key to victory. The Chiefs defense, which has its weaknesses, can still rush the passer extremely well. When you’re not running the football well, it leads to longer third downs, which tends to favor an excellent pass rush."
That being said the Pats are on the road which has been a issue this season, Belichick and Brady will have to summon all of their magic for this game.